
The image shows a portion of the surface of the reverse transcriptase enzyme of the HIV-I virus with a molecular model of an inhibitor drug compound bound to the enzyme's receptor pocket. An inhibitor drug blocks the action of the enzyme, disabling its function and thus crippling the virus. The colors mapped on the surface show extremes in the electrostatic potential of the surface and lines which represent the electrostatic field in the vicinity of the receptor pocket. In order to work, a potential inhibitor must have both the right shape and the right electrostatic characteristics to attach itself to the enzyme to disable it.
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